个人简介
程钢,1977年生,黑龙江饶河人,美国National Science Foundation Early Career Award (2015)获得者。1999年本科毕业于北京化工大学化学工程学院,获得生物化工学士学位。2005年毕业于美国明尼苏达大学双城分校,获得微生物工程硕士学位。2009年获得美国华盛顿大学西雅图分校化学工程博士学位。2009年被美国阿克隆大学化学与生物分子工程系聘为助理教授,2015年晋升为终身副教授。2016年加入美国伊利诺伊大学芝加哥分校化学工程系,担任终身副教授,从2018年起担任化学工程系研究生事务主任。2022年12月全职加入西湖大学,受聘工学院特聘研究员。
学术成果
程钢教授课题组的研究领域包括高分子化学,生物界面,生物材料设计和合成,纳米药物。课题组共发表论文80余篇,拥有已获批7项美国及国际专利。程钢教授团队完成了美国国家科学基金会,美国国防部等十余项重大项目。获得的荣誉包括美国国家自然科学基金会青年学者奖,伊利诺伊大学芝加哥分校教学奖,伊利诺伊大学芝加哥分校概念验证等。担任Journal of Functional Biomaterials编委。程钢课题组开发一系列新型高性能材料、概念和方法来解决长期存在的生物垢挑战。这些材料既可有效解决困扰多个领域(包括医疗,海洋,涂料,石化等工业)的生物垢问题,也可作为工具来探究多种生物垢的形成机制。程钢课题组同时利用实验和计算工具探索高性能抗垢材料在分子、纳米和微观尺度上的内在结构-性能关系,并建立指导材料研发的设计原则。程钢博士的多项工作被《自然-材料》、《科学》和该领域的专家所关注。
代表论文(*代表通信作者)
1. Yaqian Fan, Peilang Yang, Hongyang Ma, Yang Hu,* Gang Cheng,* and Fu-Jian Xu,* One ternary nucleic acid delivery system with smart dextran-peptide coating enables in vivo and ex vivo wound therapy, 2022, Matter, https://doi.org/10.1016/j.matt.2022.10.011
2. Li, Qingsi; Wen, Chiyu; Yang, Jing; Zhou, Xianchi; Zhu, Yingnan; Zheng, Jie; Cheng, Gang; Bai, Jie; Xu, Tong; Ji, Jian; Jiang, Shaoyi; Zhang, Lei; Zhang, Peng, Zwitterionic Biomaterials, Chemical Review, 2022, https://pubs.acs.org/doi/10.1021/acs.chemrev.2c00344
3. Kun Wang, Theo Arado, Ardith Huner, Hyang Seol, Xuan Liu, Huifeng Wang, Lena Hassan, Karthika Suresh, Sangil Kim* and Gang Cheng*, Thermoplastic zwitterionic elastomer with critical antifouling properties, Biomaterials Science, 2022, 10, 2892 – 2906
4. Huifeng Wang, Seyyedfaridoddin Fattahpour, Daniel Christiansen, Haiqing Song, Shafigh Mehraeen, Gang Cheng*, Thermoplastic polyurethane with controllable degradation and critical anti-fouling properties, Biomaterial Science, 2021, 9, 1381 - 1396.
5. Haiqing Song, Yang Hu*, Fan-Ya Qian, Gang Cheng*, Fujian Xu*, Polysaccharide-peptide conjugates: a versatile material platform for biomedical applications, 2020 Advanced Functional Materials, https://doi.org/10.1002/adfm.202005978
6. Huifeng Wang, Daniel Edward Christiansen, Shafigh Mehraeen, Gang Cheng,* Winning the fight against biofilm: A six-month study showing minimal bacterial attachment and no colony formation on zwitterionic polymers, Chemical Science, 2020,11, 4709-4721
7. Yang Hu, Megan, Young, Huifeng Wang, and Gang Cheng*, Peptide-grafted dextran vectors for efficient and high-loading gene delivery, Biomaterials Science, 2019, 7, 1543 - 1553
8. Huifeng Wang, Yang Hu, Dylan Lynch, Megan Young, Shengxi Li, Hongbo Cong , Fu-Jian Xu, and Gang Cheng*, Tunable Surface and Bulk Properties of Zwitterionic Polyurethane, ACS Applied Materials & Interfaces. 2018, DOI 10.1021/acsami.8b10450
9. Chen-Jung Lee, Huifang Wang, Megan, Young, Dylan Lynch, Hongbo Cong, and Gang Cheng*, Structure-function study of Poly (sulfobetaine 3,4-ethylenedioxythiophene) (PSBEDOT) and its derivatives, Acta Biomaterilia, 2018. 75, 161-170
10. Haiyan Wu, Chen-Jung Lee, Huifeng Wang, Yang Hu, Megan Young, Hongbo Cong* and Gang Cheng*, Highly Sensitive and Stable Zwitterionic Poly(Sulfobetaine 3,4-Ethylenedioxythiophene) (PSBEDOT) Glucose Biosensor in Complex Media, Chemical Science, 2018, 9, 2540 - 2546
11. Chen-Jung Lee, Haiyan Wu, Yang Hu, Megan, Young, Dylan Lynch, Huifang Wang, Fujian Xu, Hongbo Cong,* and Gang Cheng*, Ionic conductivity in polyelectrolyte hydrogels, ACS Applied Materials & Interfaces. 2018, 10 (6), pp 5845–5852
12. Han, Y.; Wu, H. Y.; Liu, F.; Cheng, G.*; Zhe, J.*, A Micro Resistive Pulse Immunosensor for Label-free Pathogen Measurement, Lab on a Chip 2015, DOI: 10.1039/c5lc01207d.
13. Cao B.; Lee, J. C.; Zeng, Z. P.; Cheng, F.; Xu, F. J.; Cong, H. B.*; Cheng, G.*, Electroactive Zwitterionic Poly (sulfobetaine 3,4-ethylenedioxythiophene) (PSBEDOT) with Controllable Antimicroibal and Antifouling Properties, Chemical Science 2016, 7, 1976-1981.
14. Cao, B.; Tang, Q.; Li, L. L.; Lee, C. J.; Wang, H.; Zhang, Y. Q.; Castaneda, H.*; Cheng, G.*, Integrated zwitterionic conjugated poly (carboxybetaine thiophene) as a new conducting biomaterial platform, Chemical Science 2014, 6 (1), 782 - 788.
15. Han, Y.; Wu, H. Y.; Liu, F.; Cheng, G.*; Zhe, J.*, Label-free biomarker assay in a micro resistive pulse sensor via immunoaggregation, Analytical Chemistry 2014, DOI: 10.1021/ac502270n.
16. Cao, B.; Li, L. L.; Tang, Q.; Cheng, G.*, The impact of structure on elasticity, switchability, stability and functionality of an all-in-one carboxybetaine elastomer, Biomaterials 2013, 34, (31), 7592–7600.