Dr. Jian Yang is born in 1974 in Jiangxi, China. He received his PhD at the Institute of Chemistry, the Chinese Academy of Sciences (ICCAS, China) in 2002. After 3-year postdoctoral research in the Department of Biomedical Engineering at Northwestern University (Evanston, IL USA) with Prof. Guillermo Ameer, he joined the Department of Bioengineering at the University of Texas, Arlington (UTA) as a tenure-track Assistant Professor in 2006 and then received an early promotion to the rank of tenured Associate Professor in 2011. Dr. Yang relocated to the Department of Biomedical Engineering at the Pennsylvania State University (PSU) as a tenured Associate Professor in 2012. He was promoted to the rank of Professor in 2015 and then became the Lloyd & Dorothy Foehr Huck Chair in Regeneration Engineering in 2019. Dr. Yang joined Westlake University in July 2023 as a full-time Chair Professor in Biomaterials and Regenerative Engineering.

Dr. Yang is known for his pioneering contribution to citrate chemistry and biology for the development and applications of citrate-based biomaterials and luminescent materials. Dr. Yang has published 150+ research articles and received 22 issued US patents and 100+ international patents/applications. The research topics in Dr. Yang’s lab include but not limited to: 1) Citrate chemistry and biology for biomaterials development; 2) complex tissue repair and regeneration; 3) cell metabolism and stem cell differentiation; 4) biomanufacturing; 5) bioimaging and biosensing; 6) functional biomaterials and medical devices; 7) artificial intelligence and machine learning.

Dr. Yang was a recipient of US NSF CAREER Award (2010), Outstanding Young Engineering Faculty Award at University of Texas at Arlington (2011) and PSEAS Outstanding Research Award at the Pennsylvania State University (2018). Dr. Yang is an elected Fellow of American Institute of Medical and Biological Engineering (AIMBE, 2016), a Fellow of National Academy of Inventors (NAI, 2018), a Fellow of Biomedical Engineering Society (BMES, 2020), and a Fellow of American Association for the Advancement of Science (AAAS, 2021).  Dr. Yang is the Co-Editor-in-Chief of “Bioactive Materials”, and an Associate Editor of “Science Advances”, and an Associate Editor of “Frontiers in Biotechnology and Bioengineering”. Dr. Yang is a co-founder and the Past-President of Chinese Association for Biomaterials (CAB) (2018-2022) and also the recipient of 2023 CAB Distinguished Leadership and Service Award. Dr. Yang co-invented biodegradable poly(octamethylene Citrate) (POC), the only synthetic biodegradable thermoset polyester that was ever authorized by the US FDA for the use in implantable medical devices.

1、Dingbowen Wang, Yizhu Chen, Tunan Xia, Mariana Claudino, Allison Melendez, Xingjie Ni, Cheng Dong, Zhiwen Liu*, Jian Yang*. Citric Acid-Based Intrinsic Band-Shifting Photoluminescent Materials. Research, 2023 DOI: 10.34133/research.0152.

2、Xinyu Tan, Ethan Gerhard, Yuqi Wang, Richard T. Tran, Hui Xu, Su Yan, Elias B. Rizk, April D. Armstrong, Yuxiao Zhou, Jing Du, Xiaochun Bai, Jian Yang*. Development of Biodegradable Osteopromotive Citrate-based Bone Putty. Small 2022, https://doi.org/10.1002/smll.202203003.

3、Dingbowen Wang, Michelle Laurel Kuzma, Xinyu Tan, Tong-Chuan He, Cheng Dong, Zhiwen Liu, Jian Yang*. Phototherapy and Optical Waveguides for the Treatment of Infection. Advanced Drug Delivery Reviews 2021, 179: 114036.

4、Gloria B. Kim, Virginia Aragon-Sanabria, Lauren Randolph, Hali Jiang, Joshua A. Reynolds, Becky S. Webb, Achuthamangalam Madhankumar, Xiaojun Lian, James R. Connor, Jian Yang*, Cheng Dong*. High-Affinity Mutant Interleukin-13 Targeted CAR T Cells Enhance Delivery of Clickable Biodegradable Fluorescent Nanoparticles to Glioblastoma. Bioactive Materials 2020, 5:624-635

5、Xili Lu, Sanjun Shi, Hanmei Li, Ethan Gerhard, Zhihui Lu, Xinyu Tan, Wenliang Li, Kevin M, Rahn, Denghui Xie, Guodong Xu, Fang Zou, Xiaochun Bai, Jinshan Guo, Jian Yang*. Magnesium oxide-crosslinked low-swelling citrate-based mussel-inspired tissue adhesives. Biomaterials 2020, 232, 119719

6、 Chuying Ma, Michelle L. Kuzma, Xiaochun Bai, Jian Yang*. Biomaterials-Based Metabolic Regulation in Regenerative Engineering. Advanced Science 2019, 1900819. https://doi.org/10.1002/advs.201900819

7、Chuying Ma, Xinggui Tian, Jimin Peter Kim, Denghui Xie, Xiang Ao, Dingying Shan, Qiaoling Lin, Maria Hudock, Xiaochun Bai*, Jian Yang*. Citrate-based materials fuel human stem cells by metabonegenic regulation. PNAS 2018, 115 (50): E11741-E11750

8、Dingying Shan, Sri-Rajasekhar Kothapalli, Dino J. Ravnic, Ethan Gerhard, Jimin P. Kim, Jinshan Guo, Chuying Ma, Jiazhi Guo, Li Gui, Lin Sun, Di Lu, Jian Yang*. Development of Citrate-based Dual-Imaging Enabled Biodegradable Electroactive Polymers. Advanced Functional Materials 2018, DOI:10.1002/adfm.201801787

9、Gloria B. Kim, Yongjie Chen, Weibo Kang, Jinshan Guo, Russell Payne, Hui Li, Qiong Wei, Julianne Baker, Cheng Dong, Sulin Zhang, Pak Kin Wong, Elias B. Rizk, Jiazhi Yan*, Jian Yang*. The Critical Chemical and Mechanical Regulation of Folic Acid on Neural Engineering. Biomaterials 2018,178:504-516

10、Chuying Ma, Ethan Gerhard, Di Lu, Jian Yang*. Citrate chemistry and biology for biomaterials design. Biomaterials 2018, 178:383-400

11、Dingying Shan, Chenji Zhang, Surge Kalaba, Nikhil Mehta, Gloria B. Kim, Zhiwen Liu*, Jian Yang*. Flexible biodegradable citrate-based polymeric step-index optical fiber. Biomaterials 2017, 143:142-148.

12、Jimin Peter Kim, Zhiwei Xie, Michael Creer, Zhiwen Liu*, Jian Yang*. Citrate-based fluorescent materials for low-cost chloride sensing in the diagnosis of Cystic Fibrosis. Chemical Science 2017, 8: 550-558

13、Jinshan Guo, Wei Wang, Jianqing Hu, Denghui Xie, Ethan Gerhard, Merisa Nisic, Dingying Shan, Guoying Qian, Siyang Zheng, Jian Yang*. Synthesis and characterization of anti-bacterial and anti-fungal citrate-based mussel-inspired bioadhesives. Biomaterials 2016, 85: 204-217

14、Zhiwei Xie, Yi Zhang, Li Liu, Hong Weng, Ralph P. Mason, Liping Tang, Kytai T. Nguyen, Jer-Tsong Hsieh, Jian Yang*. Development of Intrinsically Photoluminescent and Photostable Polylactones. Advanced Materials 2014, 26: 4491–4496. 

15、Jinshan Guo, Zhiwei Xie, Richard T. Tran, Denghui Xie, Dadi Jin, Xiaochun Bai, Jian Yang*. Click chemistry plays a dual role in biodegradable polymer design. Advanced Materials 2014, 26: 1906-1911

16、Mohammadreza Mehdizadeh, Hong Wen, Dipendra Gyawali, Liping Tang, Jian Yang*. Injectable Citrate-Based Mussel-Inspired Tissue Bioadhesives With High Wet Strength for Sutureless Wound Closure. Biomaterials 2012, 33: 7972-7983

17、Jian Yang*, Yi Zhang, Santosh Gautam, Li Liu, Jagannath Dey, Wei Chen, Ralph Mason, Carlos Serrano, Kevin Schug, Liping Tang. Development of aliphatic biodegradable photoluminescent polymers. PNAS 2009 106:10086-10091

18、Jagannath Dey, Hao Xu, Jinhui Shen, Paul Thevenot, Sudershan R. Gondi, Kytai T. Nguyen, Brent S. Sumerlin, Liping Tang, Jian Yang*. Development of biodegradable crosslinked urethane-doped polyester elastomers. Biomaterials 2008, 29:4637-4649

19、Jian Yang, Antonio R. Webb, Samuel J. Pickerill, Gretchen Hageman, Guillermo A. Ameer. Synthesis and evaluation of poly(diol citrates) biodegradable elastomer. Biomaterials 2006,27: 1889-1898

20、Jian Yang, Antonio Webb, Guillermo Ameer. Novel citric acid-based biodegradable elastomers for tissue engineering. Advanced Materials. 2004,16(6):511-516.

Email：yangjian07@westlake.edu.cn